CGT4859
CGT4859 is an experimental small-molecule drug from Cogent Biosciences in phase 2 trials for biliary tract cancer, aimed at FGFR2.
Overview
CGT4859 is a small-molecule drug developed by Cogent Biosciences. Its target is FGFR2 (the sponsor names FGFR2, FGFR3). The sponsor states: A selective FGFR2/3 inhibitor designed to target tumours with genetic alterations in these fibroblast growth factor receptors. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, in biliary tract cancer. The largest, NCT06777316, plans to enrol 110 participants with primary completion expected 2027-03. Status reflects the highest phase registered on ClinicalTrials.gov at the 2026-09-11 check; no efficacy results are recorded here.
Trials
topTrials recruiting now
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Latest papers
topQuery for this drug: (TITLE:"CGT4859" OR ABSTRACT:"CGT4859") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CGT4859, not a curated reading list.
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