Loading
Gas bubbles in a protein shell injected into a vein during a heart ultrasound to show the heart's pumping chamber more clearly.
GE Healthcare's Optison (NDA 020899, first approved 31 December 1997) is indicated "for use in adult and pediatric patients with suboptimal echocardiograms to opacify the left ventricle and to improve the delineation of the left ventricular endocardial borders", with the same boxed warning on serious cardiopulmonary reactions as other perflutren products. In the European Union it has been authorised since 17 May 1998 (EMEA/H/C/000166). ATC V08DA01.
Microbubbles of perflutren gas in a shell of human albumin reflect ultrasound and opacify the heart chambers.
| Region | Year | Indication |
|---|---|---|
| US | 1997 | Opacification of the left ventricle in patients with suboptimal echocardiograms · NDA 020899; GE Healthcare |
| EU | 1998 | Transpulmonary echocardiographic contrast · Authorised 17 May 1998; GE Healthcare AS |
Country and place are remembered in this browser only. A postcode is sent to OpenStreetMap's Nominatim service to find coordinates when you press the button; nothing else leaves your device.
Query for this drug: (TITLE:"Perflutren protein-type A microspheres" OR ABSTRACT:"Perflutren protein-type A microspheres" OR TITLE:"ultrasound contrast" OR ABSTRACT:"ultrasound contrast" OR TITLE:"Optison" OR ABSTRACT:"Optison" OR TITLE:"perflutren albumin microspheres" OR ABSTRACT:"perflutren albumin microspheres") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Perflutren protein-type A microspheres (ultrasound contrast), not a curated reading list.
Shares Ultrasound contrast agents (microbubbles), Elastography and contrast-enhanced ultrasound, Ultrasound and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares Ultrasound contrast agents (microbubbles), Elastography and contrast-enhanced ultrasound, Ultrasound and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares GE HealthCare and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares GE HealthCare and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares GE HealthCare and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares GE HealthCare and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares GE HealthCare and the tags contrast-agents-gaps-2026-11, diagnostic.
Shares GE HealthCare and the tags contrast-agents-gaps-2026-11, diagnostic.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/