OnCo
ideasIdea

Patients are told which trials they qualify for at every treatment decision, in writing

At each point where treatment is chosen, software checks the patient's record against open trials and the clinician must note which were discussed, so trials stop being something only some people hear about.

Fewer than one in ten adults with cancer enter trials, partly because eligibility is never checked. Structured records (mCODE) and trial registries with structured eligibility now allow automated pre-screening. The proposal is a documented eligibility check at each decision point, including trials at other centres, with the result shown to the patient in plain language and a referral pathway funded by the payer.

Hypothesis
Documented matching raises trial discussion rates to over 80% of decision points and doubles enrolment, with proportionally larger gains for minority and community patients.
Rationale
Trial offer is the single strongest determinant of enrolment; inequity in offer, not refusal, explains much under-representation.
What would test it
Cluster-randomised implementation in community oncology practices with matching software; endpoints trial discussion documentation, referral and enrolment by demographic group.
Maturity
early clinical
Who has to act
engineering
Cost to try
Medium ($1M to $50M)
Years to first evidence
3
Bottlenecks it attacks

Connected

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