A swallowable sponge test for reflux patients, offered in pharmacies
A pill on a string collects cells from the food pipe and finds Barrett's oesophagus, a precursor of cancer. Offering it in pharmacies to people on long-term heartburn drugs would find it early.
The capsule sponge (Cytosponge-TFF3) increased Barrett's detection ten-fold in primary care in BEST3; BEST4 tests screening and surveillance. Propose delivery through community pharmacies for patients on chronic acid suppression, with nurse-administered sponge, a central laboratory, and AI-assisted pathology.
- Most lethal cancers are found late · Screening exists for only a few cancers. Pancreatic, ovarian, liver, oesophageal and most lung cancers are found when cure is unlikely.
- Prevention we already have is not deployed · Around four in ten cancers are preventable with tools we already own: vaccines, tobacco control, weight, alcohol, sun and infection control.
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