OnCo
ideasIdea

Paid community advisory boards with power to change protocol burden

Before a trial is finalised, a paid panel of patients and community members from the groups the trial needs would review it and could require changes to visit schedules, procedures and materials that would deter people like them.

Sponsors convene standing, compensated community advisory boards representative of the target population for each disease programme; boards review protocols for burden (visits, biopsies, travel, language), consent materials and recruitment plans, and their recommendations must be adopted or publicly answered. Precedent from HIV research networks, where community boards are structural.

Hypothesis
Protocols reviewed by empowered community boards will have fewer research-only procedures, more flexible visit windows and higher enrolment and retention of the target groups than unreviewed protocols.
Rationale
HIV trial networks with community advisory boards achieved higher minority participation than oncology; burden is a leading reason for refusal, and those affected can identify it early.
What would test it
Within one sponsor, assign half of new protocols to board review; compare procedure counts, enrolment demographics and retention.
Maturity
early clinical
Who has to act
industry
Cost to try
Small (under $1M)
Years to first evidence
1
Bottlenecks it attacks

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