OnCo
institutionsInstitution

NRG Oncology

The US cooperative group formed from the radiation, gynaecologic, and breast trial groups; it co-led OlympiA, the trial that put a PARP inhibitor after surgery for BRCA carriers.

Formed 2014 by merger of NSABP, RTOG, and GOG. Runs radiation, breast, gynaecologic, and CNS trials in the NCI National Clinical Trials Network. Co-led OlympiA (adjuvant olaparib, with the Breast International Group and AstraZeneca) and the RTOG trials whose slides trained ArteraAI Prostate.

Location
Philadelphia, PA, US
Type
consortium
Newsweek 2026 oncology rank
Not in top 300 listing used
OnCo score
#37 · 50 points (0 Newsweek + 0 NCI + 50 from 25 linked objects) · ranking

Programmes

4top
  • NCTN cooperative group
  • OlympiA (with BIG)
  • RTOG prostate radiation trials
  • Gynaecologic oncology (former GOG)

People

4top
Bernard Fisher
Surgeon whose NSABP trials ended the radical mastectomy and established adjuvant therapy
Breast surgeryClinical trialsAdjuvant therapy

He argued that breast cancer is a systemic disease from early on, then proved in randomised trials that lumpectomy with radiation equals mastectomy and that tamoxifen after surgery, and even before cancer, saves lives.

Charles E. Geyer Jr.
Breast cancer trial leader, NRG Oncology; Professor of Medicine, University of Pittsburgh
Breast cancerAdjuvant therapyPARP inhibitors

Breast trialist who co-led OlympiA, showing adjuvant olaparib improves survival in BRCA carriers.

Deborah Watkins Bruner
Senior Vice President for Research, Emory University; NRG Oncology Vice Chair
Patient-reported outcomesRadiation oncology nursingTrial design

Nurse scientist who put patient-reported outcomes into cooperative group radiation trials.

Lori J. Pierce
Professor of Radiation Oncology and Vice Provost, University of Michigan; NRG Oncology investigator; ASCO Past President (2020-2021)
Breast radiotherapyHealth equityRadiation oncology

Lori Pierce is a breast radiation oncologist and ASCO past president focused on equity in cancer care.

Connected

29top

Pages like this

not linked directly; found by shared links

cancers

5
Cervical cancerEndometrial cancerHead and neck squamous cell carcinomaProstate cancerTriple-negative breast cancer (TNBC)

drugs

2
ApprovedAI digital pathology prognostic/predictive test
ArteraAI Prostate
ApprovedSmall-molecule PARP inhibitor
Olaparib · Lynparza

institutions

9
American Society for Radiation OncologyBreast International Group (BIG)GOG FoundationNational Cancer Institute (NIH)NSABP FoundationSociety of Gynecologic OncologyStephenson Cancer Center, OU HealthUPMC Hillman Cancer CenterWinship Cancer Institute of Emory University

trials

4
NRG-GY018 / KEYNOTE-868NRG-HN002 & NRG-HN005 (HPV+ de-escalation)OlympiAOUTBACK / ANZGOG 0902 / GOG-0274

ideas

3
A standing platform for testing new drugs with radiotherapyA statutory minimum share of public trial money for surgery and radiotherapyCore-funded radiotherapy trials infrastructure with central quality assurance

people

4
Bernard FisherCharles E. Geyer Jr.Deborah Watkins BrunerLori J. Pierce

bottlenecks

2
Surgery and radiotherapy cure most, get leastTrials enrol too few, too slowly