key papersKey paper
2021 American Thyroid Association guidelines for management of patients with anaplastic thyroid cancer
The updated American guideline for anaplastic thyroid cancer stresses molecular testing within days of diagnosis, BRAF-MEK inhibitors for BRAF-mutant disease including before surgery, multimodal therapy for resectable disease, and early goals-of-care discussions.
Overview
Evidence-based guideline covering rapid diagnosis and staging, airway management, molecular testing, surgery, radiotherapy with or without chemotherapy, BRAF-directed and other targeted therapy, immunotherapy, and palliative and supportive care for anaplastic thyroid cancer.
GuidelineChanged practice
Authors
Bible KC, Kebebew E, Brierley J, et al.
Published
Thyroid, 2021
What it means
The anaplastic thyroid cancer page's emphasis on speed, BRAF testing and neoadjuvant targeted therapy follows this guideline.
Caveats
- Evidence for most recommendations is from small series.