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Datar Cancer Genetics followed people without symptoms for a year after its tumour-cell-cluster blood test and reported that those with a positive result were far more likely to be diagnosed with cancer.
Ranade and colleagues (with Datar Cancer Genetics, Nashik) report one-year follow-up of the asymptomatic cohort from the company's earlier work (16,134 people, including 10,625 asymptomatic, among whom C-ETACs were found in 3.6%). People with detectable circulating ensembles of tumour-associated cells had a 230-fold higher one-year cancer risk than those without (P < 0.00001). In 4,419 symptomatic people later confirmed to have cancer, C-ETACs were detected in 4,101 (92.8%).
A relative risk does not say what share of positive results turned out to be cancer; with about 3.6% of people without symptoms testing positive, most positives would still not be cancer in a screening population.
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