Clinical practice guidelines for the management of biliary tract cancers 2019: The 3rd English edition
Japan's surgical society guideline for bile duct, gallbladder and ampullary cancer, the only major guideline with a section on preventive treatment.
Overview
Third English edition of the Japanese Society of Hepato-Biliary-Pancreatic Surgery guidelines, first issued in 2007 and revised in 2014. Thirty-one clinical questions cover six topics: prophylactic treatment, diagnosis, biliary drainage, surgical treatment, chemotherapy and radiation therapy, graded with GRADE as strong (14 recommendations) or weak (14), with three questions left without a recommendation.
- 31 clinical questions across six topics including prophylactic treatment.
- 14 strong and 14 weak recommendations; three questions with no recommendation.
Japanese surgeons operate on gallbladder cancer far more often than UK surgeons and their guideline addresses prevention (pancreaticobiliary maljunction, polyps) as a clinical topic, which Western guidelines do not.
- Surgical-society guideline; systemic therapy sections predate the immunotherapy trials.
- Evidence for many surgical questions is retrospective.
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