OnCo

Sign in to keep your watchlist

Your watched pages live in this browser. Sign in with an email link and OnCo keeps the same list on every device you use. Only your email address and your watchlist are stored.

Living with cancer· Appointment prep

Appointment sheet: HPV-associated vulvar squamous cell carcinoma

One page to bring and write on: your details, the questions for HPV-associated vulvar squamous cell carcinoma plus your own, the words you may hear, what to bring, the treatments the standard of care names, and room for the answers and agreed next steps. What you type stays in this browser. Print it or save it as a PDF. New to all this? Start with the first 60 days. Orientation, not medical advice.

Tick the questions to print

All of this cancer's questions start ticked. Untick what does not apply; ticks are kept in this browser. .

Your own questions

Shared with the prep pack, so questions you add there appear here too.

Print or save as PDF

Use (or Ctrl+P, Cmd+P on a Mac). To keep a copy, choose Save as PDF as the destination in the print dialog. Only the sheet prints; the controls stay on screen. Your typed notes print where you typed them; empty fields print as ruled lines to write on.

Appointment sheet

HPV-associated vulvar squamous cell carcinoma

Prepared with OnCo (onco.cc/prep/hpv-associated-vulvar-cancer/). Orientation, not medical advice; your team knows your case.

My details

Name
Date of appointment
Hospital and clinician
Who is coming with me

What I know, what is unclear, changes to discuss

Saved in this browser
What I know so far
What is unclear to me
Changes since last time

My questions

18 on the sheet
Newly diagnosed
  1. 1.What is my exact diagnosis, stage, and grade, and which tests established them?
  2. 2.Which biomarkers have been tested on my tumour (for example p16 immunohistochemistryand HPV DNA, p53 immunohistochemistry, Depth of invasion, Sentinel node status and metastasis size, PD-L1 combined positive score), and what were the results?
  3. 3.Which subtype is my cancer, and does that change the recommended treatment?
  4. 4.Is germline (inherited) genetic testing recommended for me or my family?
Precursor (usual-type VIN)
  1. 5.For my situation (precursor (usual-type vin)), which of the standard options do you recommend and why?
  2. 6.Am I a candidate for Nonavalent HPV vaccine, and what side effects should I expect?
  3. 7.How do the results of Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) and Evaluate the Efficacy, Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females apply to someone like me?
Early stage (tumour under four centimetres, clinically negative groins)
  1. 8.For my situation (early stage (tumour under four centimetres, clinically negative groins)), which of the standard options do you recommend and why?
Locally advanced disease
  1. 9.For my situation (locally advanced disease), which of the standard options do you recommend and why?
  2. 10.Am I a candidate for Cisplatin, and what side effects should I expect?
Recurrent or metastatic disease
  1. 11.For my situation (recurrent or metastatic disease), which of the standard options do you recommend and why?
  2. 12.Am I a candidate for Carboplatin, Paclitaxel / nab-paclitaxel, Bevacizumab or related drugs, and what side effects should I expect?
  3. 13.How do the results of Pembrolizumab Combination With Lenvatinib in Pts With Recurrent,Persistent,Metastatic or Locally Advanced Vulvar Cancer Not Amenable to Curative Surge and AK104 for Recurrent or Metastatic Vulvar Cancer apply to someone like me?
Any stage
  1. 14.Are there clinical trials I could join, for example of Pembrolizumab, Pembrolizumab Combination With Lenvatinib in Pts With Recurrent,Persistent,Metastatic or Locally Advanced Vulvar Cancer Not Amenable to Curative Surge, AK104 for Recurrent or Metastatic Vulvar Cancer, Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)?
  2. 15.Would a second opinion at a high-volume centre change anything, and can you help arrange it?
  3. 16.What supportive care (symptom control, nutrition, exercise, mental health, financial help) is available from the start?
  4. 17.I read that “No treatment yet differs by HPV status despite the difference in behaviour”. How does that affect my plan?
  5. 18.I read that “Recurrence of usual-type VIN after treatment is common”. How does that affect my plan?

The words I may hear

Tests and results to bring

Biomarker results to ask for: p16 immunohistochemistry (block positive) and HPV DNA, p53 immunohistochemistry (wild-type pattern), Depth of invasion (over one millimetre triggers nodal assessment), Sentinel node status and metastasis size (two millimetres threshold, GROINSS-V II), PD-L1 combined positive score (pembrolizumab), Margin status.

Bring copies of scan reports, pathology and blood results, and a list of every medicine and supplement.

The treatments I may be offered

From the standard of care recorded for this cancer; which apply depends on your stage and biomarkers. Ask which the team recommends and why.

Answers and next steps

Saved in this browser
What I was told
Agreed next steps, dates and who to call