HPV & HBV vaccination
Vaccines that prevent the viral infections behind cervical, throat, anal, and liver cancers. The most effective anti-cancer intervention ever created.
Gardasil 9 prevents ~90% of cervical cancers; Scotland and Sweden report near-zero cervical cancer in fully vaccinated cohorts. WHO targets cervical cancer elimination (90-70-90). HBV vaccination has reduced liver cancer incidence in Taiwan and elsewhere. Single-dose HPV schedules expand coverage.
How it works
Virus-like particle vaccines induce neutralising antibodies preventing persistent oncogenic infection.
- Prevents cancer outright
- Cheap at scale
- Coverage gaps, vaccine hesitancy
School-based vaccination at 12-13 with high uptake nearly abolishes cervical cancer in vaccinated cohorts, even with a vaccine covering only two HPV types. Screening intervals and the future of cervical screening can now be redesigned around vaccination status.
Vaccinating girls before they are exposed to HPV prevents most cervical cancers. Catch-up vaccination in young adults still helps, but less. Combined with HPV screening, elimination of cervical cancer as a public health problem is a realistic goal.
Women can collect their own screening sample at home with no loss of accuracy if the laboratory uses a PCR test. Sending kits directly is the most effective way to reach women who do not attend, which matters because most cervical cancers occur in under-screened women.
Latest papers
topQuery for this technology: (TITLE:"HPV vaccination" OR ABSTRACT:"HPV vaccination" OR TITLE:"HPV vaccine" OR ABSTRACT:"HPV vaccine" OR TITLE:"cervical cancer elimination" OR ABSTRACT:"cervical cancer elimination"). Results are unfiltered search hits about HPV & HBV vaccination, not a curated reading list.
Pages like this
not linked directly; found by shared links- InstitutionInternational Agency for Research on Cancer (IARC / WHO)
Shares Partha Basu, André Ilbawi, Switch every country to single-dose HPV vaccination and add catch-up to age 26, Eliminate infection-caused cancers: HPV, hepatitis B and C, H. pylori and EBV.
- TechnologyBrachytherapy
Shares Instituto Nacional de Enfermedades Neoplásicas, Cancer Institute (WIA), Adyar, Dharmais National Cancer Center, Institut National d'Oncologie, Rabat.
- TechnologyCancer registries and population surveillance
Shares Instituto Nacional de Enfermedades Neoplásicas, Cancer Institute (WIA), Adyar, Dharmais National Cancer Center, Instituto Nacional de Cancerología (Colombia).
- TermCervical precancer (CIN, HSIL/LSIL)
Shares Jade Goody, Harald zur Hausen, Basement membrane & tissue barriers, HPV DNA testing and self-sampling.
- TechnologyThermal ablation and cryotherapy for cervical precancer
Shares Single-dose HPV vaccination plus HPV self-sampling to reach WHO elimination in low-income countries, Basement membrane & tissue barriers, HPV DNA testing and self-sampling, Field cancerisation.
- TechnologyChemoprevention & risk-reducing surgery
Shares Enabling characteristic: tumour-promoting inflammation, Cancer interception vaccines, Risk factor, A delivery-science moonshot for prevention we already own.
- TermWHO Essential Medicines List for cancer
Shares Institut National d'Oncologie, Rabat, Ocean Road Cancer Institute, Uganda Cancer Institute, World Health Organization – Cancer Programme.
- TechnologyColposcopy and excisional treatment (LEEP/LLETZ, cone)
Shares Jade Goody, Basement membrane & tissue barriers, HPV DNA testing and self-sampling, Oncogenic viruses.