OnCo
termsTerm

Cervical precancer (CIN, HSIL/LSIL)

Abnormal cervical cells caused by HPV that can turn into cancer over 10-20 years. Screening finds them; a five-minute procedure removes them.

Cervical intraepithelial neoplasia grades 1-3, now reported as low-grade (LSIL, CIN1) or high-grade (HSIL, CIN2-3) squamous intraepithelial lesions; adenocarcinoma in situ is the glandular equivalent. Most LSIL regresses; ~30% of untreated CIN3 progresses to cancer within 30 years. Treated by LEEP/LLETZ excision, cold-knife cone, cryotherapy, or thermal ablation. HPV16 is the most persistent and carcinogenic type.

Cancer biology: what this kind of term is about · animated schematic, not to scale
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Cancer biology

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