Enabling characteristic: tumour-promoting inflammation

Chronic inflammation supplies growth factors, survival signals, and mutagens that help cancers start and grow.

IL-6/STAT3, TNF/NF-κB, COX-2/PGE2, inflammasomes; infection-driven cancers (HPV, HBV, H. pylori). Prevention via vaccination, anti-infectives, and aspirin; BTK inhibitors shut NF-κB in B-cell cancers.

Cancer biology: what this kind of term is about · animated schematic, not to scale