Single-dose HPV vaccination plus HPV self-sampling to reach WHO elimination in low-income countries
One shot for girls and a mail-in swab for women could hit the WHO 90-70-90 targets at a fraction of the cost of the traditional three-dose, clinic-based model.
KEN SHE showed 97.5% single-dose efficacy; self-sampled HPV PCR matches clinician sampling; thermal ablation enables screen-and-treat. Modelling (Lancet Global Health 2024) suggests single-dose schedules could make elimination feasible in most low-income settings within the century, but coverage of girls is still ~27% globally.
Pages like this
not linked directly; found by shared links- Key paperEngland's HPV programme: cervical cancer down 87% in the first cohort vaccinated at 12-13
Shares Swedish registry study: HPV vaccination almost eliminates cervical cancer when given before 17, HPV DNA testing and self-sampling, HPV & HBV vaccination, Prevention we already have is not deployed.
- IdeaSwitch every country to single-dose HPV vaccination and add catch-up to age 26
Shares Swedish registry study: HPV vaccination almost eliminates cervical cancer when given before 17, HPV & HBV vaccination, Prevention we already have is not deployed, Most of the world has almost no cancer care.
- PersonIan Frazer
Shares KEN SHE (single-dose HPV vaccine), Nonavalent HPV vaccine, HPV & HBV vaccination, Prevention we already have is not deployed.
- IdeaCommunity-tailored HPV vaccine confidence campaigns with school-based delivery
Shares Swedish registry study: HPV vaccination almost eliminates cervical cancer when given before 17, HPV & HBV vaccination, Prevention we already have is not deployed, Cervical cancer.
- PersonJian Zhou
Shares Nonavalent HPV vaccine, HPV & HBV vaccination, Prevention we already have is not deployed, Cervical cancer.
- IdeaHPV self-testing with same-day treatment as the national cervical programme
Shares HPV & HBV vaccination, Prevention we already have is not deployed, Most of the world has almost no cancer care, Cervical cancer.
- PersonJade Goody
Shares HPV DNA testing and self-sampling, HPV & HBV vaccination, Prevention we already have is not deployed, Cervical cancer.
- Key paperSelf-collected HPV samples are as accurate as clinician samples and reach women who never attend screening
Shares HPV DNA testing and self-sampling, HPV & HBV vaccination, Prevention we already have is not deployed, Most of the world has almost no cancer care.