OnCo

Cisplatin + pemetrexed

Checked 2026-09-09

Unresectable pleural mesothelioma (with or without bevacizumab); non-squamous NSCLC

One cycle

every 21 days × 6 · about 18 weeks in total
178141521Cisplatin: 75 mg/m², IntravenousCisplatinPemetrexed: 500 mg/m², IntravenousPemetrexed
21-day cycle × 6 (about 18 weeks)Intravenous

Components

DrugDoseRouteDays
Cisplatin
Cytotoxic chemotherapy (platinum)
75 mg/m²IVD1
Pemetrexed
Cytotoxic (antifolate)
500 mg/m²IVD1
Cycles
6
21-day cycle
Emetogenicity
High (>90%)
G-CSF
Not routine

Used in

Source

Vogelzang, JCO 2003

Reference doses for a typical adult from the cited protocol or label. Doses are adjusted for renal and hepatic function, age, performance status and prior toxicity, and institutional protocols vary. Verify against the current label and your local protocol before treating. Not medical advice.

Other regimens for these cancers