ctdna-roadmap
No description yet: the sentence for this tag has not been written. 6 records carry it: 6 trials.
6 records
| Cancers | Other tags | ||||
|---|---|---|---|---|---|
BESPOKE CRC NCT04264702 Natera's US study in which 1,788 people with bowel cancer had Signatera blood tests after surgery and their doctors could act on the result; it records what changed and what happened, but does not randomise anyone. | Colorectal cancer | none | none | ||
CIRCULATE-US NCT05174169 The US national trial that uses a blood test for leftover tumour DNA to decide who gets less chemotherapy and who gets more after stage III colon cancer surgery, with both questions randomised. | Colorectal cancer | none | none | ||
MERMAID-1 NCT04385368 A lung cancer trial that planned to test whether adding the immunotherapy durvalumab to chemotherapy after surgery helps people whose blood shows leftover tumour DNA; the registry lists it as complete with 89 participants. | Non-small-cell lung cancer | none | none | ||
MERMAID-2 NCT04642469 A lung cancer trial that planned to start durvalumab the moment a surveillance blood test found tumour DNA, before any scan showed relapse; the registry lists it as complete with 30 participants. | Non-small-cell lung cancer | none | none | ||
TRACC NCT04050345 A UK study following 1,000 people after bowel cancer surgery with repeated blood tests for tumour DNA, to see how well a positive predicts the cancer coming back and whether the result can guide chemotherapy. | Colorectal cancer | none | none | ||
Vanguard Study (NCI Cancer Screening Research Network) NCT06995898 The US government's first randomised study of multi-cancer blood tests: 24,000 people are being assigned to a blood test or usual care to work out how a much larger trial should be run. | none | none | none |