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protein-design

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No description yet: the sentence for this tag has not been written. 10 records carry it: 5 companies, 3 technologies, 1 person, 1 institution.

10 records
Chai Discovery
San Francisco, CA, US
Makes Chai-1 and Chai-2, open-weight structure models used for antibody and binder design.
Chai-1 / Chai-2
Structure and antibody-design models from Chai Discovery, with Chai-2 reporting high zero-shot antibody hit rates.
Cradle
Amsterdam / Zurich, NL
Cradle is a protein-engineering AI platform used by pharma to optimise antibodies and enzymes.
David Baker
Founder and Director of the Institute for Protein Design · Institute for Protein Design (University of Washington)
Nobel laureate biochemist who founded and directs the Institute for Protein Design, which builds new proteins for medicine including cancer therapeutics.
ESM3 (EvolutionaryScale)
ESM3 is a generative protein model that designed a working fluorescent protein far from any natural sequence.
EvolutionaryScale
New York, NY, US
Spun out of Meta's protein team; makes the ESM3 protein language model that generated a new fluorescent protein.
Institute for Protein Design (University of Washington)
University of Washington · Seattle, US
David Baker's institute, where de novo protein design and the RFdiffusion models come from (Nobel Prize in Chemistry 2024).
Latent Labs
London, GB
Founded by an AlphaFold co-developer to make protein design programmable; released Latent-X in 2025.
Profluent
Berkeley, CA, US
Profluent uses protein language models to design new gene editors (OpenCRISPR-1) and antibodies.
RFdiffusion / RFdiffusion2 and ProteinMPNN (Baker Lab)
The tools that design entirely new proteins to bind a chosen target, now used for cancer binders and antibodies.

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