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CD56 identifies natural killer cells, the part of the immune system that kills without needing to be taught what to look for. The same marker appears on neuroendocrine cancers, which is why it is used in diagnosis as well.
CD56 is the neural cell adhesion molecule and the marker that defines natural killer cells, which are split into CD56-bright regulatory and CD56-dim cytotoxic subsets. It is used twice over in oncology: to identify NK cells in an immune panel, and as a diagnostic stain for neuroendocrine differentiation, including small cell lung cancer, where it is also the antigen behind several antibody-drug conjugates.
In plain words · CD56 identifies natural killer cells, the part of the immune system that kills without needing to be taught what to look for. The same marker appears on neuroendocrine cancers, which is why it is used in diagnosis as well.
CD56 identifies natural killer cells, the part of the immune system that kills without needing to be taught what to look for. The same marker appears on neuroendocrine cancers, which is why it is used in diagnosis as well.
Adhesion molecule of the immunoglobulin superfamily; the defining marker of natural killer cells and expressed on neuroendocrine tissue.
No product in this corpus aims at CD56 yet. Because it sits on the outside of the cell, it can be reached from the bloodstream: antibodies flag the cell, ADCs deliver a toxin, radioligands deliver radiation, and CAR-T or bispecifics bring a T cell.
Adhesion molecule of the immunoglobulin superfamily; the defining marker of natural killer cells and expressed on neuroendocrine tissue.
Query for this target: (TITLE:"CD56" OR ABSTRACT:"CD56" OR TITLE:"NCAM1" OR ABSTRACT:"NCAM1" OR TITLE:"neural cell adhesion molecule 1" OR ABSTRACT:"neural cell adhesion molecule 1") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CD56, not a curated reading list.
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