MAGEH1
MAGEH1 (Melanoma-associated antigen H1) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response.
Overview
UniProt has no function text for Q9H213; HGNC names it "MAGE family member H1".
CIViC holds 1 clinical evidence item and 0 assertions across 1 variant, naming Gemcitabine.
- Target · the protein and the cell it sits on
- Drug · antibody, small molecule, cell or radioligand
- Effect · signal, damage or kill
In plain words · MAGEH1 (Melanoma-associated antigen H1) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response.
- 1 · What it is
MAGEH1 (Melanoma-associated antigen H1) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response.
- 2 · What goes wrong in cancer
UniProt has no function text for Q9H213; HGNC names it "MAGE family member H1". Locus Xp11.21 (HGNC).
- 3 · How drugs use it
No product in this corpus aims at MAGEH1 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
External identifiers
Sources: HGNC HGNC:24092 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q9H213 (protein name, function text, keywords and locations (REST API)); CIViC gene MAGEH1 (1 evidence items, 0 assertions, 1 variants; diseases: Bile Duct Adenocarcinoma (GraphQL API, CC0))
Biology
UniProt has no function text for Q9H213; HGNC names it "MAGE family member H1". Locus Xp11.21 (HGNC).
Notes
top- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: CIViC lists 1 therapies; CIViC holds 1 clinical evidence items on its variants. Evidence tier "clinical-evidence" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.
- Diseases the sources name that have no OnCo cancer page yet, so they are not linked: Bile Duct Adenocarcinoma.
Latest papers
topQuery for this target: (TITLE:"MAGEH1" OR ABSTRACT:"MAGEH1" OR TITLE:"MAGE family member H1" OR ABSTRACT:"MAGE family member H1" OR TITLE:"Melanoma-associated antigen H1" OR ABSTRACT:"Melanoma-associated antigen H1" OR TITLE:"APR1" OR ABSTRACT:"APR1") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about MAGEH1, not a curated reading list.