MSMB
MSMB (Beta-microseminoprotein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Prostate cancer.
Overview
UniProt has no function text for P08118; HGNC names it "microseminoprotein beta".
Open Targets scores its association with cancer at 0.63 (direct and indirect evidence; datatypes literature 0.93, animal model 0.30, genetic association 0.69, genetic literature 0.61).
- Target · the protein and the cell it sits on
- Drug · antibody, small molecule, cell or radioligand
- Effect · signal, damage or kill
In plain words · MSMB (Beta-microseminoprotein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Prostate cancer.
- 1 · What it is
MSMB (Beta-microseminoprotein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Prostate cancer.
- 2 · What goes wrong in cancer
UniProt has no function text for P08118; HGNC names it "microseminoprotein beta". Location: Secreted (UniProt).
- 3 · How drugs use it
No product in this corpus aims at MSMB yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
External identifiers
Sources: HGNC HGNC:7372 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt P08118 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000263639 (association with cancer (MONDO_0004992) 0.63; per-cancer scores at or above 0.5: prostate cancer 0.63 (GraphQL API, CC0))
Biology
UniProt has no function text for P08118; HGNC names it "microseminoprotein beta". Location: Secreted (UniProt). Locus 10q11.22 (HGNC).
- Prostate cancer: Open Targets association 0.63 with prostate cancer (MONDO_0008315)
Notes
top- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier "association-only" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.
Latest papers
topQuery for this target: (TITLE:"MSMB" OR ABSTRACT:"MSMB" OR TITLE:"microseminoprotein beta" OR ABSTRACT:"microseminoprotein beta" OR TITLE:"Beta-microseminoprotein" OR ABSTRACT:"Beta-microseminoprotein" OR TITLE:"PSP-94" OR ABSTRACT:"PSP-94" OR TITLE:"PSP57" OR ABSTRACT:"PSP57" OR TITLE:"PSP94" OR ABSTRACT:"PSP94") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about MSMB, not a curated reading list.