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Heat delivered through an endoscope to burn away the abnormal lining of the gullet in Barrett's oesophagus with dysplasia, the change that can lead to oesophageal adenocarcinoma, so normal lining grows back.
Barrx Medical's HALO ablation catheters are cleared as electrosurgical devices (product code GEI); the HALO90 Ultra catheter summary (K120431, 3 May 2012) lists Barrett's oesophagus among the indications for coagulation of sites in the gastrointestinal tract. In the sham-controlled AIM Dysplasia trial (127 patients randomised 2:1), complete eradication of dysplasia at 12 months occurred in 90.5 per cent of patients with low-grade dysplasia after ablation against 22.7 per cent with sham, and in 81.0 against 19.0 per cent with high-grade dysplasia; intestinal metaplasia was eradicated in 77.4 against 2.3 per cent, and there was less disease progression in the ablation group.
A balloon or paddle electrode array delivers a controlled dose of radiofrequency energy to a depth that destroys the Barrett's epithelium without damaging deeper layers, after which squamous lining regenerates.
Query for this technology: (TITLE:"Endoscopic radiofrequency ablation for Barrett's oesophagus" OR ABSTRACT:"Endoscopic radiofrequency ablation for Barrett's oesophagus" OR TITLE:"Barrx HALO" OR ABSTRACT:"Barrx HALO" OR TITLE:"Barrett's ablation" OR ABSTRACT:"Barrett's ablation" OR TITLE:"Radiofrequency ablation of Barrett's oesophagus" OR ABSTRACT:"Radiofrequency ablation of Barrett's oesophagus") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Endoscopic radiofrequency ablation for Barrett's oesophagus (Barrx HALO), not a curated reading list.
Shares Single-operator cholangioscopy (SpyGlass DS), Oesophageal cancer and the tag devices-gaps-2026-11.
Shares Microwave and radiofrequency ablation systems and the tag devices-gaps-2026-11.
Shares Oesophageal cancer and the tag devices-gaps-2026-11.
Shares Barrett's oesophagus, Oesophageal and junctional adenocarcinoma.
Shares Oesophageal and junctional adenocarcinoma, Oesophageal cancer.
Shares Oesophageal and junctional adenocarcinoma, Oesophageal cancer.
Shares Oesophageal and junctional adenocarcinoma, Oesophageal cancer.
Shares Oesophageal and junctional adenocarcinoma, Oesophageal cancer.
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