Decentralised and hybrid clinical trials
Running parts of a trial at home or locally, with telehealth, home nursing, and remote monitoring, so patients far from big centres can take part.
Accelerated by the pandemic and FDA guidance (2023-24), decentralised elements include telehealth visits, home infusion or blood draws, local imaging and labs, direct-to-patient drug shipping, and wearables. Vendors: Science 37 (acquired by eMed 2024), Medable, THREAD, Lightship, Walgreens/CVS trial services (partly wound down). Oncology adoption lags other areas because of IV drugs and imaging, but hybrid designs (local labs, remote consent) are common.
How it works
Decentralised trials combine remote consent and data capture, mobile nursing networks, and local investigator sites coordinated through a central protocol.
- Access and diversity
- Retention
- IV regimens and imaging need sites
- Data quality and oversight
- Vendor consolidation
Latest papers
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