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Fucoidan is a sugar-like compound from brown seaweed sold as an anticancer supplement. Small studies suggest it may ease fatigue and help some people stay on chemotherapy, but there is no proof it controls cancer. It thins the blood, so it can add to anticoagulants.
Fucoidan is a sulfated polysaccharide from the cell walls of brown seaweeds. Memorial Sloan Kettering's About Herbs summary lists antitumour, antiangiogenic, antiviral and anti-inflammatory effects in laboratory and animal work. In small human studies, fucoidan given alongside treatment helped people with advanced cancer continue chemotherapy and regulated fatigue, lowered inflammatory cytokines, and, combined with transarterial chemoembolisation, was reported to improve control of hepatocellular carcinoma and preserve liver function; in locally advanced rectal cancer on chemoradiotherapy it was associated with better quality of life, less rash and less fatigue. A small study in breast cancer found no clinically significant interaction with letrozole or tamoxifen. Because fucoidan has anticoagulant and antithrombotic activity, MSK warns it may increase bleeding risk with warfarin or heparin. Diarrhoea has been reported and stopped when fucoidan was stopped.
Sulfated fucose polymers bind growth factors and selectins and modulate platelets and immune cells in laboratory models.
Query for this technology: (TITLE:"Fucoidan" OR ABSTRACT:"Fucoidan" OR TITLE:"brown seaweed extract" OR ABSTRACT:"brown seaweed extract") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Fucoidan (brown seaweed extract), not a curated reading list.
Shares MGN-3 (rice bran arabinoxylan, BioBran), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology and the tags complementary, supportive-care.
Shares MGN-3 (rice bran arabinoxylan, BioBran), Letrozole (and other aromatase inhibitors), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology and the tags complementary, supportive-care.
Shares Tamoxifen, Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Tamoxifen, Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Letrozole (and other aromatase inhibitors), Tamoxifen, Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology and the tags complementary, supportive-care.
Shares Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Tamoxifen, Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology and the tags complementary, supportive-care.
Shares Tamoxifen, Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
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