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Black seed is a cooking spice and traditional remedy, also promoted against cancer. Small trials found that the seeds lowered fever with low white cells in children with brain cancers and that a gel reduced radiation skin reactions in breast cancer, but larger studies are needed. High doses may harm the liver, and it may weaken warfarin.
Nigella sativa seeds, known as black seed or black cumin, are used in cooking and in traditional medicine for inflammation, infections and cancer. Memorial Sloan Kettering's About Herbs summary cites small clinical trials for asthma, allergy, dyspepsia, diabetes and fatty liver, and anticancer effects of thymoquinone in the laboratory. In cancer care, oral seeds lowered the incidence of febrile neutropenia and shortened hospital stay in children with brain tumours, and a topical gel decreased the severity of acute radiation dermatitis in women with breast cancer; MSK says larger studies are needed. Contact dermatitis and a case of eosinophilia with systemic symptoms after topical oil are reported, and high doses may cause liver damage, with human data lacking. Black seed inhibits CYP2D6 and CYP3A4 in vitro and thymoquinone inhibited warfarin activity, both of unknown clinical significance.
Thymoquinone is antioxidant, anti-inflammatory and pro-apoptotic in cancer cell lines.
Query for this technology: (TITLE:"Black seed Nigella sativa and thymoquinone" OR ABSTRACT:"Black seed Nigella sativa and thymoquinone" OR TITLE:"Black cumin" OR ABSTRACT:"Black cumin" OR TITLE:"Black seed oil" OR ABSTRACT:"Black seed oil") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Black seed (Nigella sativa) and thymoquinone, not a curated reading list.
Shares Baikal skullcap (Scutellaria baicalensis), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Bitter melon (Momordica charantia), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology and the tags complementary, supportive-care.
Shares Baikal skullcap (Scutellaria baicalensis), Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
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