Loading
The Gonzalez regimen combines pig pancreatic enzyme capsules, a strict diet, supplements and coffee enemas. In a controlled study in inoperable pancreatic cancer, people who chose it lived a median of 4.3 months against 14.0 months for those who chose chemotherapy, and had worse quality of life.
The regimen, tailored by its practitioner for each person, centred on oral porcine pancreatic enzymes thought to attack cancer, plus diets, vitamin and mineral supplements, animal organ extracts and coffee enemas, up to about 150 pills a day. The NCI sponsored a randomised trial against chemotherapy in inoperable pancreatic cancer; because most eligible patients refused randomisation, it became a controlled observational study (Chabot et al., Journal of Clinical Oncology 2010). Of 55 patients, 23 chose gemcitabine-based chemotherapy and 32 chose the enzyme regimen. Median survival was 14.0 months with chemotherapy and 4.3 months with enzymes (adjusted hazard ratio for death 6.96), one-year survival was 56 per cent against 16 per cent, and quality of life was better with chemotherapy; a median is the midpoint, so half of each group lived longer than its figure. Memorial Sloan Kettering's About Herbs page on proteolytic enzymes, which also covers the commercial enzyme mixtures (Wobenzym, Wobe-Mugos) used in Germany, reports conflicting data in other cancers, a randomised trial that did not support enzymes for preventing mucositis, and meta-analyses suggesting possible benefit for radiation skin reactions that need confirming. Enzymes containing bromelain may add to the effect of anticoagulants. The NCI PDQ summary describes the earlier uncontrolled pilot study that prompted the trial.
Proposed that pancreatic enzymes digest cancer cells and 'detoxify' the body; the controlled study found the opposite of the claimed effect on survival.
Query for this technology: (TITLE:"Gonzalez regimen" OR ABSTRACT:"Gonzalez regimen" OR TITLE:"pancreatic proteolytic enzymes" OR ABSTRACT:"pancreatic proteolytic enzymes" OR TITLE:"Gonzalez protocol" OR ABSTRACT:"Gonzalez protocol" OR TITLE:"Proteolytic enzyme therapy" OR ABSTRACT:"Proteolytic enzyme therapy") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Gonzalez regimen (pancreatic proteolytic enzymes), not a curated reading list.
Shares Gerson therapy, coffee enemas and 'detox' regimens, Alternative medicine used instead of standard treatment, Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Di Bella multitherapy, Alternative medicine used instead of standard treatment, Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Selected Vegetables and Sun's Soup, Alternative medicine used instead of standard treatment, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Gerson therapy, coffee enemas and 'detox' regimens, Alternative medicine used instead of standard treatment, Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Alternative medicine used instead of standard treatment, Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies, Pancreatic ductal adenocarcinoma and the tags complementary, supportive-care.
Shares Alternative medicine used instead of standard treatment, Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Alternative medicine used instead of standard treatment, Misinformation and unproven therapies, Gemcitabine, Pancreatic ductal adenocarcinoma and the tags complementary, supportive-care.
Shares Alternative medicine used instead of standard treatment, Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies and the tags complementary, supportive-care.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/