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Peppermint oil has trial evidence for irritable bowel symptoms and indigestion. In people with cancer, small studies suggest that breathing in peppermint oil may reduce chemotherapy nausea, and a herbal mouthwash with peppermint and chamomile eased mouth sores after stem cell transplant, but none of this is yet established. It can worsen heartburn.
Peppermint (Mentha piperita) is used orally for digestive complaints and topically and by inhalation for aches and nausea. Memorial Sloan Kettering's About Herbs summary cites meta-analyses showing reduced irritable bowel symptoms and trials for dyspepsia and colonoscopy spasm. For nausea, inhaled peppermint oil helped in pregnancy and after cardiac surgery, though other findings suggest aromatherapy is only as effective as placebo for postoperative nausea. In cancer, inhalation may reduce chemotherapy-induced nausea and vomiting in children and adults, and an herbal mouthwash containing chamomile and peppermint alleviated oral mucositis after haematopoietic stem cell transplantation. People with gallstones, hiatus hernia or reflux should consult a doctor first; heartburn, nausea and dermatitis are reported. Peppermint oil inhibits several CYP enzymes in vitro, raised felodipine levels, has variable effects on cyclosporine, can increase skin absorption of topical fluorouracil, and minor to moderate interactions with docetaxel and cisplatin have been reported.
Menthol relaxes gut smooth muscle by blocking calcium channels and acts on cold-sensing TRPM8 receptors; inhaled aroma may act partly through expectation.
Query for this technology: (TITLE:"Peppermint and peppermint oil" OR ABSTRACT:"Peppermint and peppermint oil") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Peppermint and peppermint oil, not a curated reading list.
Shares Chamomile, Lavender (oral and aromatherapy), Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Aromatherapy, Lavender (oral and aromatherapy), Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Antiemetics for chemotherapy-induced nausea and vomiting, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Antiemetics for chemotherapy-induced nausea and vomiting, Evidence-based integrative oncology, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Evidence-based integrative oncology, Docetaxel, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Evidence-based integrative oncology, Fluorouracil (5-FU), Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
Shares Evidence-based integrative oncology, Toxicity and quality of life are undervalued, Cisplatin and the tags complementary, supportive-care.
Shares Evidence-based integrative oncology, Docetaxel, Toxicity and quality of life are undervalued and the tags complementary, supportive-care.
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