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TranscriptFormer and rBio (CZI virtual cell models)

CZI's open cross-species cell models and a reasoning model trained on them.

TranscriptFormer (2025) trained on 112M cells across 12 species; rBio uses virtual cell model outputs as a teacher for an LLM that reasons about gene perturbations.

Generic schematic · not to scale · placeholder for the ai computation front
Flagged finding · Neural network

How it works

TranscriptFormer is a generative transformer over cells, distilled into an LLM.

Strengths
  • Open, cross-species
Limitations
  • Early
Since
2025

Latest papers

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Latest papers · live from Europe PMC
Open in Europe PMC

Query for this technology: (TITLE:"TranscriptFormer and rBio" OR ABSTRACT:"TranscriptFormer and rBio" OR TITLE:"CZI virtual cell models" OR ABSTRACT:"CZI virtual cell models") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about TranscriptFormer and rBio (CZI virtual cell models), not a curated reading list.

Connected

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