Pneumonectomy
Removing an entire lung. Now rare in cancer surgery because the cost in breathing capacity is high.
Used for central lung tumours that cannot be cleared by lobectomy or sleeve resection. Extrapleural pneumonectomy (lung, pleura, diaphragm and pericardium) was tried for mesothelioma but the MARS 1 trial suggested harm and practice shifted to lung-sparing pleurectomy/decortication, itself questioned by MARS 2. Mortality is 5-10%, and long-term cardiopulmonary limitation is common.
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