Efficacy and Safety of Prophylactic Cranial Irradiation Versus MRI Surveillance in Patients With Limited-stage Small Cell Lung Cancer Who Achieved Remission Aft

Efficacy and Safety of Prophylactic Cranial Irradiation Versus MRI Surveillance in Patients With Limited-stage Small Cell Lung Cancer Who Achieved Remission After First-line Chemoradiotherapy is a phase 3, randomised interventional study registered as NCT04829708 by Shandong Cancer Hospital and Institute, with a registry enrolment figure of 534 participants, started 2021-04-26 and due to reach its primary completion in 2026-04-15. Interventions recorded: MRI Surveillance; Prophylactic Cranial Irradiation. Conditions listed: Limited Stage Small Cell Lung Cancer. Primary outcome: Overall survival (OS). Lung eligibility wording from the registry: "Histological or cytological confirmation of LS-SCLC before first-line chemoradiotherapy (according to the staging system of the Veterans' Affairs Lung Study Group (VALSG), Appendix 2)；". Sites: China. No results are recorded here; the registry entry is the source.