IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma (IOB-013 / KN-D18)
A phase 3 trial testing IO102-IO103 in melanoma, active and no longer recruiting.
Overview
IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma (IOB-013 / KN-D18) is a phase 3 interventional study registered as NCT05155254, led by IO Biotech with Syneos Health and Merck Sharp & Dohme, and active but no longer recruiting when checked on 2026-09-11. Official title: An Open-label, Randomised, Phase 3 Clinical Trial of IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Patients With Previously Untreated, Unresectable, or Metastatic (Advanced) Melanoma (IO102-IO103-013 / MK3475-D18). Planned enrolment is 407 participants (actual). The study started in 2022-05-17 and primary completion is expected in 2025-05-30. No results have been posted on ClinicalTrials.gov.
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