Loading
A phase 3 trial of carboplatin, cisplatin, durvalumab, etoposide and other drugs in lung cancer, run by NRG Oncology, now recruiting.
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT05624996 by NRG Oncology, with a registry enrolment figure of 474 participants, started 2023-07-12 and due to reach its primary completion in 2031-10-15. Interventions recorded: Carboplatin; Cisplatin; Computed Tomography; Durvalumab; Etoposide; Image Guided Radiation Therapy; Nab-paclitaxel; Osimertinib; Paclitaxel; Pemetrexed; Positron Emission Tomography; Questionnaire Administration; Stereotactic Body Radiation Therapy. Conditions listed: Locally Advanced Lung Non-Small Cell Carcinoma; Stage IIB Lung Cancer AJCC v8; Stage III Lung Cancer AJCC v8. Primary outcome: Overall survival (OS); Progression-free survival (PFS). Lung eligibility wording from the registry: "* Pathologically (histologically or cytologically) proven diagnosis of non-operable stage IIB or III, node positive (American Joint Committee on Cancer \[AJCC\] eighth edition) non-small cell lung cancer (NSCLC) with known PD-L1 status prior to registration". Sites: Canada, United States. No results are recorded here; the registry entry is the source.
Shares Unresectable stage III non-small-cell lung cancer, Etoposide, Pemetrexed, Durvalumab and the tag lung-deep-dive.
Shares Etoposide, Pemetrexed, Durvalumab, Topoisomerase-I inhibitors (and ADC payloads) and the tag lung-deep-dive.
Shares Nab-paclitaxel, Pemetrexed, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel and the tag lung-deep-dive.
Shares Unresectable stage III non-small-cell lung cancer, Pemetrexed, Durvalumab, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Unresectable stage III non-small-cell lung cancer, Nab-paclitaxel, Pemetrexed, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Nab-paclitaxel, Pemetrexed, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel and the tag lung-deep-dive.
Shares Unresectable stage III non-small-cell lung cancer, Pemetrexed, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel and the tag lung-deep-dive.
Shares Nab-paclitaxel, Pemetrexed, SBRT / SABR (stereotactic radiotherapy), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.