First-line Trastuzumab, Gemcitabine, Cisplatin and Nivolumab in Advanced HER2- Positive Biliary Tract Cancer: a Multicenter, Open-label, Single-arm Phase Ib/II Trial (HERBOT)
A phase 1/2 trial of trastuzumab, nivolumab, gemcitabine and cisplatin in gallbladder cancer and other biliary tract cancers, run by Yonsei University, now recruiting.
Overview
First-line Trastuzumab, Gemcitabine, Cisplatin and Nivolumab in Advanced HER2- Positive Biliary Tract Cancer: a Multicenter, Open-label, Single-arm Phase Ib/II Trial (HERBOT) is a phase 1/2 interventional study registered as NCT05749900 by Yonsei University, with a registry enrolment figure of 44 participants, started 2023-05-12 and due to reach its primary completion in 2026-02-28. Interventions recorded: Trastuzumab+Nivolumab+Gemcitabine+Cisplatin. Conditions listed: HER2 Positive Advanced/Metastatic/Nonresectable Biliary Tract Cancer. Gallbladder cancer is named in the registry entry: "1. Subjects with histologically- or cytologically-confirmed biliary tract cancer (including intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, and gall bladder cancer)". Sites: South Korea. No results are recorded here; the registry entry is the source.
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