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This study compares usual chemotherapy with or without durvalumab in a selected high-risk group of early breast cancers. It asks whether adding immune treatment lowers the chance of a cancer-related event.
This study compares usual chemotherapy with or without durvalumab in a selected high-risk group of early breast cancers. It asks whether adding immune treatment lowers the chance of a cancer-related event.
Interventional study registered as NCT06058377, sponsored by National Cancer Institute (NCI). Registry phase: 3. Registry enrollment is 3,680 participants (estimated). Registry status checked October 10, 2026: recruiting. UCSF lists this study as closed to local enrollment; local availability and overall registry status are separate. See the registry for full eligibility and current sites.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-10. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Doxorubicin, Cyclophosphamide, Paclitaxel / nab-paclitaxel and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Doxorubicin, Cyclophosphamide, Paclitaxel / nab-paclitaxel and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Paclitaxel / nab-paclitaxel, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Paclitaxel / nab-paclitaxel, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
Shares UCSF Helen Diller Family Comprehensive Cancer Center, Breast cancer (all types) and the tags ucsf-breast-coverage, interventional.
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