A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
A phase 3 trial testing Ficlatuzumab in head and neck squamous cell carcinoma, now recruiting.
Overview
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma is a phase 3 interventional study registered as NCT06064877, led by AVEO Pharmaceuticals, and recruiting when checked on 2026-09-11. Official title: A Multicenter, Randomised, Double Blind, Placebo - Controlled, Phase 3 Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV -Negative Head and Neck Squamous Cell Carcinoma. (FIERCE-HN). Planned enrolment is 410 participants (estimated). The study started in 2024-01-11 and primary completion is expected in 2027-08. No results have been posted on ClinicalTrials.gov.
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