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A phase 2/3 trial of nab-paclitaxel, gemcitabine and cisplatin in pancreatic cancer, run by Alliance for Clinical Trials in Oncology, active but no longer recruiting.
The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer is a phase 2/3, randomised interventional study registered as NCT06115499 by Alliance for Clinical Trials in Oncology, with a registry enrolment figure of 10 participants, started 2024-08-13 and due to reach its primary completion in 2029-01-15. Interventions recorded: Nab paclitaxel; Gemcitabine; Cisplatin; Magnetic Resonance Imaging; Computed Tomography; Biospecimen Collection. Conditions listed: Pancreatic Acinar Cell Carcinoma; Pancreatic Adenocarcinoma; Pancreatic Adenosquamous Carcinoma; Pancreatic Carcinoma; Pancreatic Ductal Adenocarcinoma; Pancreatic Squamous Cell Carcinoma; Stage IV Pancreatic Cancer AJCC v8. Primary outcome: Overall response rate (ORR) (Phase II); Overall Survival (OS) (Phase III). Pancreatic eligibility wording from the registry: "* Metastatic pancreatic adenocarcinoma". Sites: United States. No results are recorded here; the registry entry is the source.
Shares BRCA or PALB2-mutant pancreatic ductal adenocarcinoma, Nab-paclitaxel, Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares BRCA or PALB2-mutant pancreatic ductal adenocarcinoma, Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Nab-paclitaxel, Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Nab-paclitaxel, Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites), Gemcitabine and the tag pancreatic-deep-dive.
Shares Nab-paclitaxel, Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Nab-paclitaxel, Pancreatic cancer trials open today (registry snapshot and UK sites), Gemcitabine, Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Nab-paclitaxel, Pancreatic cancer trials open today (registry snapshot and UK sites), Gemcitabine, Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Nab-paclitaxel, Pancreatic cancer trials open today (registry snapshot and UK sites), Gemcitabine, Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.