Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer

Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer is a phase 2, randomised interventional study registered as NCT06698757 by Yugui Lian, with a registry enrolment figure of 96 participants, started 2024-11-15 and due to reach its primary completion in 2027-11-15. Interventions recorded: Sintilimab. Conditions listed: Colorectal Cancer. Primary outcome: the pathological complete response rate (pCR). Colorectal eligibility wording from the registry: "* has pathologically confirmed colon cancer or upper rectal cancer (with the lower edge of the tumor more than 10 cm from the anal verge); clinical stage cT3/T4 or N+". Sites: China. No results are recorded here; the registry entry is the source.