Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer

Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer is a phase 3, randomised interventional study registered as NCT07372300 by Shih-Kai Hung, with a registry enrolment figure of 126 participants, started 2025-09-23 and due to reach its primary completion in 2027-12-31. Interventions recorded: Hyperthermia. Conditions listed: Locally Advanced Rectal Carcinoma. Primary outcome: Down-staging Rate. Colorectal eligibility wording from the registry: "Initial pathological diagnosis of adenocarcinoma of the rectum". Sites: Taiwan. No results are recorded here; the registry entry is the source.