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A phase 2 trial in colorectal cancer, run by Sun Yat-sen University, not yet recruiting.
Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal Cancer is a phase 2, randomised interventional study registered as NCT07405736 by Sun Yat-sen University, with a registry enrolment figure of 124 participants, started 2026-02-24 and due to reach its primary completion in 2027-06-01. Interventions recorded: maintenance therapy plus lubiprostone; maintenance therapy. Conditions listed: Colorectal Cancer Metastatic; Peritoneal (Metastatic) Cancer; Peritoneal Metastasis; Colorectal Cancer (CRC); MSS Metastatic Colorectal Cancer. Primary outcome: 1-year Progression-Free Survival (PFS) Rate. Colorectal eligibility wording from the registry: "* Histologically confirmed colon/rectal adenocarcinoma with molecular status confirmed as pMMR or MSS". No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
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