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A phase 1/2 trial of pemetrexed, paclitaxel / nab-paclitaxel, docetaxel, bevacizumab and other drugs in lung cancer, run by Shanghai JMT-Bio Inc., not yet recruiting.
SYS6090 Combination Therapy in Advanced Lung Cancer is a phase 1/2, interventional study registered as NCT07472647 by Shanghai JMT-Bio Inc., with a registry enrolment figure of 596 participants, started 2026-02-28 and due to reach its primary completion in 2029-02-28. Interventions recorded: SYS6090 + pemetrexed + platinum-based chemotherapy; SYS6090 + paclitaxel + platinum-based chemotherapy; SYS6090 + docetaxel; SYS6090 + pemetrexed + bevacizumab + platinum-based chemotherapy; SYS6090 + SYS6010; SYS6090 + etoposide + platinum-based chemotherapy; SYS6090 + chemotherapy or other anticancer therapy. Conditions listed: Non-Small Cell Lung Cancer; Small Cell Lung Cancer. Primary outcome: Dose-Limiting Toxicity (DLT) (Phase Ib); Adverse Events (AEs) (Phase Ib); Objective response rate (ORR) (Phase II). Lung eligibility wording from the registry: "Histologically or cytologically confirmed unresectable locally advanced (stage IIIB/IIIC) or metastatic (stage IV) non-small cell lung cancer (NSCLC) according to the AJCC/UICC Cancer Staging System, 8th edition, or extensive-stage small cell lung cancer (SCLC), not amenable to curative surgical res". No results are recorded here; the registry entry is the source.
Shares Etoposide, Anti-angiogenic therapy, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Docetaxel, Pemetrexed, Bevacizumab, Anti-angiogenic therapy and the tag lung-deep-dive.
Shares Bevacizumab, Anti-angiogenic therapy, Lung cancer trials open today (registry snapshot), Monoclonal antibodies and the tag lung-deep-dive.
Shares Docetaxel, Pemetrexed, Anti-angiogenic therapy, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares SYS6010, Docetaxel, Lung cancer trials open today (registry snapshot), Cytotoxic chemotherapy and the tag lung-deep-dive.
Shares Etoposide, Pemetrexed, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Docetaxel, Anti-angiogenic therapy, Lung cancer trials open today (registry snapshot), Monoclonal antibodies and the tag lung-deep-dive.
Shares Bevacizumab, Anti-angiogenic therapy, Lung cancer trials open today (registry snapshot), Monoclonal antibodies and the tag lung-deep-dive.