A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A phase 3 trial testing INCB161734 in pancreatic ductal adenocarcinoma, now recruiting.
Overview
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma is a phase 3 interventional study registered as NCT07522073, led by Incyte with Qiagen Manchester, and recruiting when checked on 2026-09-11. Official title: A Randomised, Double-Blind, Phase 3 Study of Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma (DAWN-303). Planned enrolment is 588 participants (estimated). The study started in 2026-04-09 and primary completion is expected in 2028-09-15. No results have been posted on ClinicalTrials.gov.
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