Efficacy and Safety of SBRT Plus Gemcitabine, Cisplatin, and Sintilimab as First-Line Treatment for Unresectable Biliary Tract Cancer
A phase 2 trial of sintilimab, gemcitabine and cisplatin with radiotherapy in gallbladder cancer and other biliary tract cancers, run by Eastern Hepatobiliary Surgery Hospital, not yet recruiting.
Overview
Efficacy and Safety of SBRT Plus Gemcitabine, Cisplatin, and Sintilimab as First-Line Treatment for Unresectable Biliary Tract Cancer is a phase 2, randomised interventional study registered as NCT07638501 by Eastern Hepatobiliary Surgery Hospital, with a registry enrolment figure of 123 participants, started 2026-06-15 and due to reach its primary completion in 2028-06-15. Interventions recorded: Sintilimab + GC, SBRT 7Gy✖️5 QD. Conditions listed: Biliary Tract Cancer (BTC). Gallbladder cancer is named in the registry entry: "3. Histologically or cytologically confirmed, unresectable advanced or metastatic adenocarcinoma of biliary tract, including cholangiocarcinoma (intrahepatic or extrahepatic) and gallbladder carcinoma.". Sites: China. No results are recorded here; the registry entry is the source.
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