Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib as First-Line Therapy for Advanced HER2-Positive/HER2-Low Biliary Tract Cancer
A phase 2 trial of trastuzumab rezetecan, adebrelimab and lenvatinib in gallbladder cancer and other biliary tract cancers, run by Peking Union Medical College Hospital, now recruiting.
Overview
Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib as First-Line Therapy for Advanced HER2-Positive/HER2-Low Biliary Tract Cancer is a phase 2 interventional study registered as NCT07670273 by Peking Union Medical College Hospital, with a registry enrolment figure of 70 participants, started 2026-04-29 and due to reach its primary completion in 2027-04-29. Interventions recorded: Trastuzumab Rezetecan, Adebrelimab, Lenvatinib. Conditions listed: Biliary Tract Neoplasms Immunotherapy. Gallbladder cancer is named in the registry entry: "3. Locally advanced or metastatic cholangiocarcinoma, including cholangiocarcinoma (intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma) and gallbladder cancer, which has been confirmed by pathological histo". Sites: China. No results are recorded here; the registry entry is the source.
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