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A phase 1/2 trial in colorectal cancer, run by SOTIO Biotech a.s., now recruiting.
A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer is a phase 1/2, randomised interventional study registered as NCT07693751 by SOTIO Biotech a.s., with a registry enrolment figure of 100 participants, started 2026-08-12 and due to reach its primary completion in 2027-11-29. Interventions recorded: SOT109. Conditions listed: Colorectal Cancer (Locally Advanced or Metastatic). Primary outcome: Part A: Maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of SOT109; Part B: Optimal dose of SOT109 for subsequent clinical trials; Part B: Objective Response Rate (ORR) of SOT109. Colorectal eligibility wording from the registry: "* Direct (conjugated) bilirubin is within normal limits (≤ULN), and". Sites: Moldova, United States. No results are recorded here; the registry entry is the source.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.