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Cancers
Central nervous system germ cell tumours (germinoma and non-germinomatous)
Data

Cancers·Central nervous system germ cell tumours (germinoma and non-germinomatous)

DataCentral nervous system germ cell tumours (germinoma and non-germinomatous)

Back to the Central nervous system germ cell tumours hub →30 connected records

Every connected record, the notes, the JSON, Markdown and RDF twins, and where the record came from and when it was checked.

Overview What it is Finding it Treating it Evidence The science Where you are Living with it What is coming Data

Data

Related pages

30

Direct links plus the targets, companies, and technologies of this cancer's products.

Similar pages

not linked directly; found by shared links

Cancer
SHH-activated medulloblastoma
Shares The 2021 WHO classification of tumours of the central nervous system: a summary, Thiotepa, SIOP Europe (European Society for Paediatric Oncology), Late effects and survivorship toxicity and the tags subtype-page, cns, paediatric.
Cancer
Group 3 and group 4 medulloblastoma (non-WNT/non-SHH)
Shares The 2021 WHO classification of tumours of the central nervous system: a summary, Thiotepa, SIOP Europe (European Society for Paediatric Oncology), Late effects and survivorship toxicity and the tags subtype-page, cns, paediatric.
Cancer
WNT-activated medulloblastoma
Shares The 2021 WHO classification of tumours of the central nervous system: a summary, SIOP Europe (European Society for Paediatric Oncology), Late effects and survivorship toxicity, Medulloblastoma and the tags subtype-page, cns, paediatric.
Cancer
Paediatric high-grade glioma (excluding diffuse midline glioma)
Shares The 2021 WHO classification of tumours of the central nervous system: a summary, Re-irradiation, SIOP Europe (European Society for Paediatric Oncology), Late effects and survivorship toxicity and the tags subtype-page, cns, paediatric.
Cancer
Ependymoma
Shares SIOP Europe (European Society for Paediatric Oncology), Late effects and survivorship toxicity, Atypical teratoid/rhabdoid tumour (ATRT), Survivorship and late effects are neglected and the tags cns, paediatric.
Cancer
Intermediate-risk neuroblastoma
Shares SIOP Europe (European Society for Paediatric Oncology), Late effects and survivorship toxicity, Children's Oncology Group (COG), MRI and the tags subtype-page, paediatric.
Cancer
Low-risk neuroblastoma (INRG very low and low risk, including stage MS)
Shares SIOP Europe (European Society for Paediatric Oncology), Late effects and survivorship toxicity, Children's Oncology Group (COG), MRI and the tags subtype-page, paediatric.
Cancer
Spinal cord tumours (intramedullary and intradural)
Shares The 2021 WHO classification of tumours of the central nervous system: a summary, Brain and spinal cord tumours (all types), MRI, Proton therapy and the tags subtype-page, cns.

technologies

9

Allogeneic stem cell transplantation Autologous stem cell transplant (high-dose therapy)Cytotoxic chemotherapy IMRT / IGRT (modern external beam)Intravesical therapy (BCG, chemotherapy, devices, gene and viral therapy)MRI Platinum agents Proton therapy Topoisomerase-I inhibitors (and ADC payloads)

targets

1

KMT2A (MLL) rearrangement

drugs

5

ApprovedCytotoxic chemotherapy (platinum)

ApprovedCytotoxic chemotherapy (platinum)

Cisplatin · Platinol (generic)

ApprovedTopoisomerase II inhibitor (podophyllotoxin derivative)

Etoposide · VePesid / Etopophos / Toposar

ApprovedCytotoxic chemotherapy (alkylating agent)

Ifosfamide · Ifex

ApprovedAlkylating agent (ethylenimine)

Thiotepa · Tepadina

companies

2

Adienne Pharma & Biotech Bristol Myers Squibb

institutions

2

Children's Oncology Group (COG)SIOP Europe (European Society for Paediatric Oncology)

terms

3

Alpha-fetoprotein (AFP)Late effects and survivorship toxicity Re-irradiation

trials

2

ACNS0122 ACNS1123

bottlenecks

2

Rare and paediatric cancers without markets Survivorship and late effects are neglected

key papers

4

ACNS1123: response-based reduced radiotherapy for localised CNS non-germinomatous germ cell tumours ACNS1123: response-based reduced-dose whole-ventricular radiotherapy for localised germinoma SIOP CNS GCT 96: outcomes for children and adults with intracranial germinoma treated with radiotherapy alone or chemotherapy plus reduced radiotherapy The 2021 WHO classification of tumours of the central nervous system: a summary

Machine-readable versions

The same record for scripts and assistants; checked 2026-09-17. Data CC BY-NC 4.0, attribute “Data from OnCo (onco.cc)”.

JSON with neighbours Markdown context RDF Turtle Sections with routes and counts API root

Not yet reviewedNeeds expert (clinical) and patient advocate review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link cancer subtypes to their siblings and name parents i… · diff · file

Wikipedia

Sources & links

Wikipedia
NCI PDQ: childhood CNS germ cell tumours
SIOP CNS GCT 96 germinoma results (Neuro-Oncology 2013)

subtype-page cns paediatric

Data

JSON · ·

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Machine-readable versions of Central nervous system germ cell tumours (germinoma and non-germinomatous)

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Markdown context for language models
RDF Turtle for this record (its triples, relations and owl:sameAs; the IRI of this record is https://onco.cc/cancers/cns-germ-cell-tumours/)
Section plan: the ten sections of this record with routes, anchors and counts
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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id cns-germ-cell-tumours.

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