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NCI CDAS: NLST and PLCO screening trial data

NCI CDAS holds the lung screening trial images that trained Sybil and most lung-nodule AI.

NLST enrolled 53,000 smokers; its CT archive is the standard for lung cancer risk models.

Holds
Low-dose CT images and outcomes from the National Lung Screening Trial, and PLCO screening data, available to approved researchers.
Licence
Data access request
Maintainer
NCI

Key papers

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rctNew England Journal of Medicine 2011changed practice
NLST: yearly low-dose CT scans cut lung cancer deaths in heavy smokers

For people with a heavy smoking history, an annual low-dose CT scan is one of the few screening tests proven to reduce cancer deaths. Most abnormal scans are not cancer, so screening must be paired with careful nodule management. It does not apply to never-smokers or light smokers.

Connected

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technologies

1
Sybil (MIT/MGH lung cancer risk from CT)

institutions

1
National Cancer Institute (NIH)

key papers

1
NLST: yearly low-dose CT scans cut lung cancer deaths in heavy smokers