Matrisome Bio is a Cambridge, Massachusetts start-up that aims treatments at the scaffolding around tumour cells, the extracellular matrix, rather than at the cells themselves. It is developing a radioactive medicine for lung cancer that has spread.
Matrisome Bio, Inc., of Cambridge, Massachusetts, describes itself as a seed-stage start-up delivering payloads to disease-associated components of the extracellular matrix of tumours and metastases, using a toolbox of nanobody-based binders. In fiscal year 2026 the National Cancer Institute funded its SBIR project on an extracellular matrix-targeted theranostic radiopharmaceutical for metastatic lung cancer (5R44CA298532-02, USD 1,013,647).
Investors not recorded; see the round sources.
| Round | Year | Amount | Source |
|---|---|---|---|
| Grant · NCI SBIR (R44) award 5R44CA298532-02: Development of an extracellular matrix-targeted theranostic radiopharmaceutical for metastatic lung cancer | 2026 | $1M | reporter.nih.gov |
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