APBB1IP
APBB1IP (Amyloid beta A4 precursor protein-binding family B member 1-interacting protein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. This dossier gathers the 0 products (0 approved), 0 trials, 0 pathways and 0 resistance routes in the corpus that involve it, with external identifiers so it can be joined to UniProt, ChEMBL, Open Targets and the rest of biology.
Biology
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion. Location: Cell membrane; Cell projection, lamellipodium; Cell junction, focal adhesion; Cytoplasm, cytoskeleton (UniProt). Locus 10p12.1 (HGNC).
External identifiers
Built from HGNC, Ensembl, UniProt and ChEMBL idsProducts by modality and phase
Browse products →No product in the corpus is aimed at this target yet.
Trials
Evidence ranking →No trial in the corpus names this target or one of its products.
Resistance routes
Unaddressed routes →The resistance atlas has no route that names this target.
Pathways
Pathway-to-drug matrix →No pathway diagram carries this target as a node.
Companion diagnostics
Assay registry →No companion diagnostic in the registry measures this target.
Preclinical models
All models →No model entry for this target yet; check the cancer entries on the models page.
Open questions
All open questions →No open questions recorded for this target yet. Suggest one.
Literature
Preprints →Query for this target: (TITLE:"APBB1IP" OR ABSTRACT:"APBB1IP" OR TITLE:"amyloid beta precursor protein binding family B member 1 interacting protein" OR ABSTRACT:"amyloid beta precursor protein binding family B member 1 interacting protein" OR TITLE:"Amyloid beta A4 precursor protein-binding family B member 1-interacting protein" OR ABSTRACT:"Amyloid beta A4 precursor protein-binding family B member 1-interacting protein" OR TITLE:"RARP1" OR ABSTRACT:"RARP1" OR TITLE:"PREL1" OR ABSTRACT:"PREL1" OR TITLE:"INAG1" OR ABSTRACT:"INAG1") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about APBB1IP, not a curated reading list.
Export
The dossier as machine-readable JSON: identifiers from HGNC, Ensembl, UniProt and ChEMBL, products with status, trials, pathways, hotspots, open questions and assays. The full entity record is in the open API at /api/v1/entities/apbb1ip.json. Licence CC BY-NC 4.0.