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SSX2 (SSX family member 2) is a protein that switches other genes on and off. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role. Tied to Sarcomas and Synovial sarcoma. This dossier gathers the 1 product (0 approved), 2 trials, 0 pathways and 0 resistance routes in the corpus that involve it, with external identifiers so it can be joined to UniProt, ChEMBL, Open Targets and the rest of biology.
Could act as a modulator of transcription. Location: Nucleus (UniProt). Locus Xp11.22 (HGNC).
| Modality | Phase 1 |
|---|---|
| Cell therapy 1 |
| Trial | Setting | Result | Products | ||
|---|---|---|---|---|---|
| 1 | Planned | A Phase 1 Study With Expansion of Patient-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-601) Administered To Patients With Locally Advanced Unresectable or Metastatic Pancreatic Cancer (PANACEA) | - | ||
| 1 | Recruiting | A Phase 1 Study of Patient-Derived Multi-Tumor-Associated Antigen-Specific T Cells (MT-601) Administered to Patients With Relapsed or Refractory Non-Hodgkin and Hodgkin Lymphoma (APOLLO) | - |
No recorded escape route names this target.
No pathway diagram carries this target as a node.
No companion diagnostic in the registry measures this target.
No model entry for this target yet; check the cancer entries on the models page.
No open questions recorded for this target yet. Suggest one.
Query for this target: (TITLE:"SSX2" OR ABSTRACT:"SSX2" OR TITLE:"SSX family member 2" OR ABSTRACT:"SSX family member 2" OR TITLE:"HOM-MEL-40" OR ABSTRACT:"HOM-MEL-40" OR TITLE:"HD21" OR ABSTRACT:"HD21" OR TITLE:"MGC3884" OR ABSTRACT:"MGC3884" OR TITLE:"MGC15364" OR ABSTRACT:"MGC15364") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about SSX2, not a curated reading list.
The dossier as machine-readable JSON, at /api/v1/dossiers/ssx2.json: identifiers from HGNC, Ensembl, UniProt and ChEMBL, products with status, trials, pathways, hotspots, open questions and assays. The full entity record is in the open API at /api/v1/entities/ssx2.json. Licence CC BY-NC 4.0.