Bomedemstat
Bomedemstat is an experimental small-molecule drug from Merck Sharp & Dohme in phase 3 trials for myeloproliferative neoplasms, with its target not yet stated publicly.
Overview
Bomedemstat (MK-3543, IMG-7289) is a small-molecule drug developed by Merck Sharp & Dohme. Its molecular target is not stated in the ClinicalTrials.gov intervention record, and OnCo has not confirmed one from the sponsor's pipeline page. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, including the phase 3 study NCT06351631 (A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)), in myeloproliferative neoplasms. The largest, NCT06351631, plans to enrol 400 participants with primary completion expected 2034-12-04. Status reflects the highest phase registered on ClinicalTrials.gov at the 2026-09-11 check; no efficacy results are recorded here.
Trials
topTrials recruiting now
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Landmark trials
Latest papers
topQuery for this drug: (TITLE:"Bomedemstat" OR ABSTRACT:"Bomedemstat" OR TITLE:"MK-3543" OR ABSTRACT:"MK-3543" OR TITLE:"IMG-7289" OR ABSTRACT:"IMG-7289") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Bomedemstat, not a curated reading list.
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