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CP-383 is an experimental small molecule from Tasca Therapeutics, in phase 1 trials for colorectal cancer, small cell lung cancer and head and neck squamous cell carcinoma and other cancers.
CP-383 is a small molecule from Tasca Therapeutics. The registry describes CP-383 as an anti-cancer agent that inhibits pyrimidine synthesis in cancer cells; the company calls it a first-in-class inhibitor from its auto-palmitoylation platform. Its furthest stage is phase 1, for colorectal cancer, small cell lung cancer, head and neck squamous cell carcinoma and bladder cancer. ClinicalTrials.gov registers it in one study linked below. Phase 1/2 NCT07030257 recruiting (registry, 3 Nov 2026). Whether it works in people has not been established unless a trial below reports it.
The registry describes CP-383 as an anti-cancer agent that inhibits pyrimidine synthesis in cancer cells; the company calls it a first-in-class inhibitor from its auto-palmitoylation platform.
1.CP-383 slips into a pocket on its target.
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Query for this drug: (TITLE:"CP-383" OR ABSTRACT:"CP-383") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CP-383, not a curated reading list.
Shares Bladder & urothelial cancer, Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.
Shares Bladder & urothelial cancer, Head and neck squamous cell carcinoma, Colorectal cancer and the tag pipeline.
Shares Head and neck squamous cell carcinoma, Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.
Shares Small-cell lung cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Head and neck squamous cell carcinoma, Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.
Shares Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.
Shares Bladder & urothelial cancer, Head and neck squamous cell carcinoma, Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.
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